This book constitutes the refereed proceedings of five workshops co-located with SAFECOMP 2018, the 37th International Conference on Computer Safety, Reliability, and Security, held in VästerÃ¥s, Sweden, in September 2018. The 28 revised full papers and 21 short papers presented together with 5 introductory papers to each workshop were carefully reviewed and selected from 73 submissions. This year's workshops are: ASSURE 2018 â Assurance Cases for Software-Intensive Systems; DECSoS 2018 â ERCIM/EWICS/ARTEMIS Dependable Smart Embedded and Cyber-Physical Systems and Systems-of-Systems; SASSUR 2018 â Next Generation of System Assurance Approaches for Safety-Critical Systems; STRIVE 2018 â Safety, securiTy, and pRivacy In automotiVe systEms; and WAISE 2018 â Artificial Intelligence Safety Engineering. The chapter 'âBoxing Cleverâ: Practical Techniques for Gaining Insights into Training Data and Monitoring Distribution Shift' is available open access under an Open GovernmentLicense via link.springer.com.